18th Global Neuroscience Conference
CUHK Shenzhen Research Institute, China
Title: Structural and functional MRI correlates of poststroke depression
Biography: Wai Kwong Tang
Depression is common following an acute stroke. Poststroke Depression (PSD) has notable impacts on the function recovery and quality of life of stroke survivors. Incidence decreased across time after stroke but prevalence of PSD tends to be stable. Many studies have explored the association between lesion location and the incidence of PSD. For example, lesions in frontal lobe, basal ganglia and deep white matter have been related with PSD. Furthermore, cerebral microbleeds and functional changes in brain networks have also been implicated in the development of PSD. In this study, evidences of such association between the above structural and functional brain changes and PSD will be reviewed. Specifically, PSD is related to fronto-subcortial circuit infarcts, vascular markers of large and small vessael diseases as well as abnormal white matter integrity and functioning connectivity in various brain regions.