Neuroendocrinology & Hormones
Neuroendocrinology is the study of the intricate interactions between the nervous system and the endocrine system, focusing on how hormones regulate brain function and influence behavior. The hypothalamus, a small but crucial brain structure, acts as the primary control center, linking the brain to the endocrine system via the pituitary gland. Through this connection, the brain communicates with various glands, including the adrenal glands, thyroid gland, and gonads (testes and ovaries), to regulate essential physiological processes such as growth, metabolism, stress response, reproduction, and mood.Hormones play a critical role in brain development, cognition, and emotional regulation. For example, cortisol, the primary stress hormone, is released by the adrenal glands in response to signals from the hypothalamus-pituitary-adrenal (HPA) axis. While short-term cortisol release is essential for adaptive responses to stress, chronic overactivation of the HPA axis can lead to anxiety, depression, cognitive impairment, and neurodegenerative diseases.
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